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Pentadeca Arginate (PDA)

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Pentadeca Arginate (PDA)

Pentadeca Arginate (PDA) is a synthetic peptide that is often used for its regenerative and anti-inflammatory properties. It is a derivative of the more well-known BPC-157, with an added arginate salt that is said to enhance its stability and bioavailability.

Accelerated Tissue Repair and Healing
Enhanced Collagen Synthesis
Improved Blood Flow (Angiogenesis)
Anti-Inflammatory Effects

from $186/mo.*

*with Membership, consult, and provider approval

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⚠️ Currently Not Available in Kentucky, Louisiana, Ohio & Virginia
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The science behind
Pentadeca Arginate (PDA)

Pentadeca Arginate (PDA) is a synthetic peptide that shares a core structure with BPC-157, a pentadecapeptide naturally found in human gastric juice, with the key addition of an arginate salt to enhance its stability and bioavailability. The physiological mechanism of action for PDA is largely based on the extensive research conducted on BPC-157, which demonstrates a pleiotropic beneficial effect on various tissues. PubMed studies suggest that BPC-157, and by extension PDA, promotes tissue repair through several pathways. A crucial mechanism is its ability to stimulate angiogenesis, the formation of new blood vessels, which improves blood flow and oxygen delivery to damaged areas. This pro-angiogenic effect is often linked to the upregulation of key genes like Egr-1 and growth factors such as vascular endothelial growth factor (VEGF). Furthermore, research highlights its influence on the nitric oxide (NO) system, demonstrating a unique ability to modulate NO levels to promote healing and counteract both NO-system overstimulation and blockade. PDA's regenerative effects also extend to the gastrointestinal tract, where it supports the healing of mucosal integrity and counteracts damage from various agents. By these multifaceted actions, PDA enhances the body's natural healing processes, reduces inflammation, and protects tissues from injury.
Science behind Pentadeca Arginate (PDA)

The mechanism of
Pentadeca Arginate (PDA)

Pentadeca Arginate (PDA) is a peptide that works by helping your body heal itself. It's an improved version of a peptide found naturally in your stomach. It helps your body create new blood vessels, which brings more blood and oxygen to injured areas, speeding up the healing process. This peptide also calms inflammation, which reduces pain and swelling, and it's especially good at repairing the lining of your stomach and intestines. Essentially, PDA gives your body's natural repair system a powerful boost, allowing it to fix damaged tendons, ligaments, muscles, and gut lining more effectively.
INGREDIENTS
Pentadeca Arginate (PDA)
BENEFITS
Accelerated Tissue Repair: PDA is highly regarded for its ability to speed up the healing of various tissues, including tendons, ligaments, muscles, and bones. This makes it particularly beneficial for athletes and individuals recovering from injuries or surgery.
  • Anti-Inflammatory Properties: It helps to reduce both localized and systemic inflammation, which can alleviate pain and discomfort associated with injuries, chronic conditions, and general tissue damage.
  • Enhanced Collagen Synthesis: PDA promotes the production of collagen, a crucial protein for the structural integrity of skin, tissues, and bones, leading to quicker and more complete recovery and potential anti-aging effects.
  • .Improved Blood Flow: It promotes the formation of new blood vessels (angiogenesis), which enhances blood circulation and oxygen delivery to damaged areas, a critical process for efficient healing.
Doctors Say:
Providers might prefer Pentadeca Arginate (PDA) over other reparative medications due to its unique and multifaceted mechanism of action that promotes healing across multiple biological systems. Unlike many medications that focus on a single aspect of repair (e.g., pain relief, anti-inflammatory), PDA works at a cellular level to promote angiogenesis (the formation of new blood vessels), which is crucial for delivering oxygen and nutrients to damaged tissues. Furthermore, it modulates the nitric oxide (NO) system to create an environment conducive to healing while also directly enhancing the body's natural regenerative processes. This pleiotropic effect allows it to not only accelerate the repair of tendons, ligaments, and muscles but also to protect and heal the gastrointestinal tract and provide anti-inflammatory benefits. This broad-spectrum reparative capability, combined with a seemingly low side-effect profile, makes PDA a versatile and potentially more effective option for providers seeking to treat a wide range of tissue injuries and inflammatory conditions.
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  • Once Daily
  • Subcutaneous Injection
  • 250mcg
60%
more affordable than our competitors.
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NAD+Med / IV Clinics
25mg injection$59 per shot$7 per shot*
1000mg (40 treatments)$2,360$249 (supplies included)**
Private At-Home UseNoYes
US FDA-Inspected PharmacyNoYes
*with Membership
**1000mg vial (40 × 25mg injections)
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