EDUCATION CENTER

Does TRT Cause Acne?

Oilier skin and acne are among the more common dermatologic effects.

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Does TRT cause acne?

It can. Androgens increase sebum, so oily skin and acne (back, chest, or face) show up in a subset of men, especially after a dose increase or with high peaks on infrequent injections.

Skincare, dose timing changes, and sometimes dermatology care help. Cystic or scarring acne is a reason to adjust the protocol, not to add random internet “PCT” drugs.

FAQs

Does acne mean my estrogen is high?

Not necessarily. Acne is often androgen-driven. Do not start an aromatase inhibitor for pimples without labs and a clinician.

References

  1. 1. Bhasin S, et al. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744.

  2. 2. Mulhall JP, et al. Evaluation and Management of Testosterone Deficiency: AUA Guideline. J Urol. 2018;200(2):423-432.

  3. 3. Lincoff AM, et al. Cardiovascular Safety of Testosterone-Replacement Therapy (TRAVERSE). N Engl J Med. 2023;389:107-117.

  4. 4. U.S. Food and Drug Administration. Testosterone Information.

  5. 5. Bhasin S, et al. Testosterone Replacement in Aging Men: An Endocrine Society Scientific Statement. J Clin Endocrinol Metab.

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